NURSING ANM AND GNM

Detailed explanation-1: -Malignant hypertension is blood pressure that is 180/120 or higher. This can cause fibrinoid necrosis in the blood vessels of the heart, brain, kidneys and other organs. Other conditions that can cause fibrinoid necrosis include: Autoimmune diseases such as rheumatoid arthritis, lupus and rheumatic fever.

Detailed explanation-2: -Malignant hypertension usually presents in a younger age group (35–50 years) and is characterized pathologically by fibrous endarteritis in the interlobular arteries of the kidney and fibrinoid necrosis in the walls of a proportion of the efferent glomerular arterioles.

Detailed explanation-3: -Abstract. It has been shown in previous studies that fibrinoid necrosis not only occurs in connective tissue and in vessel walls, but can also be observed in the liver cells under special conditions and can also be provoked experimentally.

Detailed explanation-4: -Fibrinoid necrosis is a pattern of cell death characterized by endothelial damage and exudation of plasma proteins (especially fibrin).

Detailed explanation-5: -The pink material resembling fibrin seen in the wall of this arteriole is indicative of the process of fibrinoid necrosis as a consequence of hypertensive emergency (malignant hypertension) when systolic pressure is ≥180 and/or diastolic pressure ≥120 mmHg along with signs of acute or ongoing end-organ damage.