NURSING ANM AND GNM

Detailed explanation-1: -For total IgG, the half-life found was 25.8 days; for IgG1 it was 29.7 days; for IgG2 it was 26.9 days; and for IgG3 it was 15.7 days. The results are similar to those reported for endogeneous IgG. Half-lives for antibodies to S.

Detailed explanation-2: -Important in this regard is the long serum half-life of IgG. Humans have four IgG subclasses (IgG1–4), three of which have a serum half-life of roughly 3 weeks (IgG1, 2, 4), whereas it is 1 week for IgG3 (Morell et al., 1970).

Detailed explanation-3: -Ig M is the largest immunoglobulin that possesses 900 kDa molecular weight with IgA being 150 kDa, IgE being 190 kDa and IgD is not yet identified.

Detailed explanation-4: -IgG half-lives in piglet serum range from 6.5 to 22.5 days.