NURSING ANM AND GNM

NURSING EXAM QUESTIONS

PATHOLOGY AND GENETICS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Regarding apoptosis, which of the following is FALSE?
A
It is the responsible for programmed destruction of cells during embryogenesis.
B
Occurs in pathologic atrophy in parenchymal organs after duct destruction.
C
Associated with inflammation
D
Cell death by cytotoxic T cells.
Explanation: 

Detailed explanation-1: -Apoptosis does not trigger inflammation, whereas another form of cell death called necrosis-in which the cell membrane is ruptured-is often associated with inflammation (Kerr et al., 1972).

Detailed explanation-2: -The answer is that cells that constitute lee express BCL two will be more prone to get killed. This isn’t true at all.

Detailed explanation-3: -Apoptosis, in contrast to necrosis, is not harmful to the host and does not induce any inflammatory reaction. The principal event that leads to inflammatory disease is cell damage, induced by chemical/physical injury, anoxia or starvation.

Detailed explanation-4: -J Biol Chem. 1998 Sep 18; 273(38):24470-8.

There is 1 question to complete.