NURSING ANM AND GNM

NURSING EXAM QUESTIONS

PATHOLOGY AND GENETICS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The following are proinflammatory type of cells which induce the following cytokines.
A
IL2 and IL 12
B
IL10 and IL13
C
IL12 and IL4
D
all of the above
Explanation: 

Detailed explanation-1: -IL-2 is a pro-inflammatory cytokine secreted by activated CD4 + and CD8 + T-cells that plays a pivotal role in regulatory T-cells (Treg cells) biology and immune response homeostasis [72]. IL-2 was characterized as a powerful T-cell growth factor, promoting the expansion of CD4 + and CD8 + T activated antigen.

Detailed explanation-2: -IL-12 can aid in the activation and regulation of several cytotoxic immune cells including macrophages, natural killer cells, and T cells, thus making it a ‘pro-inflammatory cytokine’.

Detailed explanation-3: -Interleukin-12 (IL-12) is a heterodimeric pro-inflammatory cytokine that induces the production of interferon- (IFN-), favours the differentiation of T helper 1 (TH1) cells and forms a link between innate resistance and adaptive immunity.

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