NURSING EXAM QUESTIONS
PHARMACOGNOSY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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fluorescein isothiocyanate
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Fluoro iso tetra carbol.
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Fluorine iso ti chloro.
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None of the above.
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Detailed explanation-1: -Fluorescein isothiocyanate (FITC) is a derivative of fluorescein used in wide-ranging applications including flow cytometry. First described in 1942, FITC is the original fluorescein molecule functionalized with an isothiocyanate reactive group (−N=C=S), replacing a hydrogen atom on the bottom ring of the structure.
Detailed explanation-2: -Fluorescein isothiocyanate (FITC)-labeled antibodies are widely used as primary antibodies in the tissue cross-reactivity (TCR) studies for the development of therapeutic antibodies.
Detailed explanation-3: -Fluorescein-5-isothiocyanate (FITC) is a fluorescence dye and belongs to the xanthene dyes. FITC is used for labeling of different biomolecules, e.g. immunoglobulins, lectins and other proteins, peptides, nucleic acids, nucleotides; oligo-and polysaccha-rides.