NURSING EXAM QUESTIONS
PHARMACOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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An acute increase in Paco2 of 10 mm Hg will result in a decrease in pH of
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0.01 pH unit
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0.02 pH unit
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0.04 pH unit
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0.08 pH unit
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Explanation:
Detailed explanation-1: -The CO2 accumulates in the blood, so PCO2 rises, usually above 45 mmHg. This causes a decrease in blood pH, often reducing it below 7.35. To compensate for this decrease, the body has designed several mechanisms. If the respiratory centers are working, then they try to increase the rate and depth of ventilation.
Detailed explanation-2: -When a person hyperventilates they exhale more carbon dioxide than normal. As a result the carbon dioxide concentration in the blood is reduced and the bicarbonate/carbonic acid equilibrium shifts to the left. The corresponding drop in H3O+ concentration causes an increase in pH.
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