NURSING EXAM QUESTIONS
PHARMACOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Atropine intoxication effects can be overcome by increasing endogenous Acetylcholine. Which drug should be given as therapy?
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Ipratropium
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Physostigmine
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Methacholine
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Acetylcholine
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Explanation:
Detailed explanation-1: -Physostigmine, given as an atropine antidote by slow intravenous injection of 1 to 4 mg (0.5 to 1 mg in pediatric populations), rapidly abolishes delirium and coma caused by large doses of atropine.
Detailed explanation-2: -Physostigmine is a medication most commonly used to manage and treat antimuscarinic toxicity and glaucoma. It is a tertiary amine and a reversible cholinergic medication most commonly used to manage and treat antimuscarinic toxicity and glaucoma.
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