NURSING EXAM QUESTIONS
PHARMACOLOGY
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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glipizide
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pioglitazone
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glyburide
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glucotrol
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Detailed explanation-1: -Glyburide appears to lower the blood glucose acutely by stimulating the release of insulin from the pancreas, an effect dependent upon functioning beta cells in the pancreatic islets. The mechanism by which glyburide lowers blood glucose during long-term administration has not been clearly established.
Detailed explanation-2: -DiaBeta and Micronase belong to a group of medications known as sulfonylureas. They work by stimulating the pancreas to release more insulin. This helps lower blood glucose levels. DiaBeta and Micronase are classified as non-micronized forms of glyburide.
Detailed explanation-3: -Glyburide, along with others in its class of sulfonylureas, exerts its mechanism of action based on increasing insulin secretion from beta cells in the pancreas. [7] Specifically, sulfonylureas bind to the SUR1 receptors in the membranes of the beta cells of potassium ATP-dependent channels.