NURSING ANM AND GNM

Detailed explanation-1: -The level of cellular cGMP is determined largely by the balance between its synthesis by guanylyl cyclase and breakdown by PDEs, although the transporters may play a role in some cells.

Detailed explanation-2: -Phosphodiesterase inhibitors are medications that cause blood vessels to relax and widen, improving circulation and lowering blood pressure. That makes them useful for treating a wide range of medical conditions, including problems with your skin and joints, your heart and lungs, and even sexual dysfunction.