NURSING ANM AND GNM

NURSING EXAM QUESTIONS

PHARMACOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Phase 2 in action potential
A
depolarizing phase
B
repolarizing phase
C
plateau phase
D
overshoot phase
Explanation: 

Detailed explanation-1: -Phase 2 is the plateau phase of the cardiac action potential. Membrane permeability to calcium increases during this phase, maintaining depolarization and prolonging the action potential.

Detailed explanation-2: -During the plateau phase, the permeability of potassium ions decreases, significantly slowing the efflux of potassium ions out of the muscle. From: Biofluid Mechanics (Third Edition), 2022.

Detailed explanation-3: -Slow Calcium Channel The Slow Calcium Channels are most responsible for the Plateau Phase, because they allow a long time-scale influx of positive ions which exactly balances the initially low efflux of potassium.

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