NURSING EXAM QUESTIONS
PHARMACOLOGY
Question
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Phase 2 in action potential
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depolarizing phase
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repolarizing phase
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plateau phase
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overshoot phase
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Explanation:
Detailed explanation-1: -Phase 2 is the plateau phase of the cardiac action potential. Membrane permeability to calcium increases during this phase, maintaining depolarization and prolonging the action potential.
Detailed explanation-2: -During the plateau phase, the permeability of potassium ions decreases, significantly slowing the efflux of potassium ions out of the muscle. From: Biofluid Mechanics (Third Edition), 2022.
Detailed explanation-3: -Slow Calcium Channel The Slow Calcium Channels are most responsible for the Plateau Phase, because they allow a long time-scale influx of positive ions which exactly balances the initially low efflux of potassium.
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