NURSING ANM AND GNM

NURSING EXAM QUESTIONS

PHARMACOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The combination of tetracycline and antacids causes tetracycline to not work.
A
pharmacological antagonism
B
physiological antagonism
C
chemical antagonism
D
None of the above
Explanation: 

Detailed explanation-1: -Avoid taking milk, dairy products, antacids containing aluminum, calcium, or magnesium (eg, Maalox®, Tums®), or supplements containing iron, zinc, or sodium bicarbonate. This may keep tetracycline from working properly. Do not drink milk or eat dairy products with this medicine.

Detailed explanation-2: -Achieving adequate serum concentrations of tetracyclines may be impaired by antacids that contain aluminum, calcium, magnesium, iron, zinc, or sodium bicarbonate. Thus, certain foods high in these cations, as well as some dairy products, may interfere with absorption.

Detailed explanation-3: -Tetracycline absorption in the gastrointestinal tract can be impaired by sodium bicarbonate, aluminum hydroxide, magnesium hydroxide, iron, calcium salts, milk and other dairy products. Therefore in addition to milk, antacids and kaolin products reduce Page 2 absorption.

There is 1 question to complete.