NURSING ANM AND GNM

Detailed explanation-1: -p50-The p50 is the pressure at which hemoglobin is 50% saturated (27 mmHg on the X-axis). Arterial blood-Hemoglobin is approximately 100% saturated at an oxygen pressure of 100 mmHg.

Detailed explanation-2: -Patients with sickle cell disease have a variable Hb level that may range from 7.0 to 11.0 g/dL in their steady state condition.

Detailed explanation-3: -p50 is the oxygen tension when hemoglobin is 50 % saturated with oxygen. When hemoglobin-oxygen affinity increases, the oxyhemoglobin dissociation curve shifts to the left and decreases p50. When hemoglobin-oxygen affinity decreases, the oxyhemoglobin dissociation curve shifts to the right and increases p50 (Figure 1).