NURSING ANM AND GNM

Detailed explanation-1: -Physical dependence is a state of adaptation that is manifested by a drug class specific withdrawal syndrome that can be produced by abrupt cessation, rapid dose reduction, decreasing blood level of the drug, and/or administration of an antagonist.

Detailed explanation-2: -The main difference between tolerance and dependence is that tolerance refers to the body getting used to taking a substance and requiring higher doses. Dependence, however, refers to the physical or psychological symptoms that occur that make someone feel like they must continue taking a substance.

Detailed explanation-3: -Drug dependence is defined as a psychic and physical state of the person characterized by behavioral and other responses resulting in compulsions to take a drug, on a continuous or periodic basis in order to experience its psychic effect and at times to avoid the discomfort of its absence.