NURSING ANM AND GNM

NURSING EXAM QUESTIONS

PHARMACOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following can cause aright ward shift of the oxyhemoglobindissociation curve?
A
Methemoglobinemia
B
Carbo-xyhemoglobinemia
C
Hypothermia
D
Pregnancy
Explanation: 

Detailed explanation-1: -The right shift in the oxygen dissociation curve is due to an increase in partial pressure of carbon dioxide or a decrease in the pH.

Detailed explanation-2: -The oxyhaemoglobin curve is shifted to the right when there is high PCO2, low PO2, high H+ concentration (low pH) and high temperature. Hence, Option D is correct.

Detailed explanation-3: -Fetal hemoglobin (HbF) is a principal oxygen carrier in the blood of preterm and term neonates. Compared to adult hemoglobin, it has a significantly higher affinity for oxygen and its oxyhemoglobin dissociation curve (ODC) is left-shifted accordingly.

Detailed explanation-4: -The O2-hemoglobin dissociation curve shifts to the right as a result of increased tissue PCO2, increased temperature, and decreased tissue pH.

There is 1 question to complete.