NURSING ANM AND GNM

NURSING EXAM QUESTIONS

PHARMACOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of these Diabetic treatments has the highest risk of causing Hypoglycaemia?
A
Metformin
B
Sulphonylureas (such as Gliclazide)
C
Thiazolidinediones (such as Pioglitazone)
D
DPP-4 inhibitors (such as Sitagliptin)
Explanation: 

Detailed explanation-1: -The long-acting sulphonylureas chlorpropamide and glibenclamide are associated with a greater risk of hypoglycaemia; for this reason they should be avoided in the elderly and shorter-acting alternatives, such as gliclazide or tolbutamide, should be used instead.

Detailed explanation-2: -Gliclazide can sometimes cause your blood sugar to go too low. The name for this is hypoglycaemia, or a “hypo". Early warning signs of low blood sugar include: feeling hungry.

Detailed explanation-3: -Metformin, thiazolidinediones, and acarbose, oral antidiabetic drugs that decrease insulin resistance or postprandial glucose absorption, are associated with a low risk of hypoglycaemia.

There is 1 question to complete.