NURSING EXAM QUESTIONS
PHARMACOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Short-acting bronchodilator is used as a preventer medicine in asthmatic patients
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b2-adrenoceptor agonist prevents late phase in asthma caused by release of cytokine
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b2-adrenoceptor agonist increases cAMP level, leading to airway relaxation
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Decrease in cAMP prevents mast cell degranulation
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Detailed explanation-1: -Hexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent. An inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD.
Detailed explanation-2: -Stimulation of beta-2 receptors in the lungs causes bronchodilation, the desired clinical effect. Albuterol has been used in humans to inhibit uterine contractions during premature labor. Stim-ulation of beta-2 receptors on skeletal muscle cells causes increased contractility and may lead to muscle tremors.
Detailed explanation-3: -These agents act by engaging the beta-2 adrenergic receptors on smooth muscle of bronchial tissue, relieving bronchospasm and reducing airway resistance. They also act on smooth muscle of the vascular system, intestines and uterus.