NURSING EXAM QUESTIONS
TOXICOLOGY
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Aspirin has an LD50 of 200 mg/kg. How many 50 mg aspirin tablets would a 100 kg human have to consume before there was a 50% chance that they would die?
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2000 pills
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800 pills
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20 pills
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400 pills
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Explanation:
Detailed explanation-1: -LD stands for “Lethal Dose". LD50 is the amount of a material, given all at once, which causes the death of 50% (one half) of a group of test animals.
Detailed explanation-2: -Median lethal concentration (LC50) was determined using the formulae; LC50 = LC100-∑ conc. Diff. × mean % mortality / % control.
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