NURSING EXAM QUESTIONS
TOXICOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Cyanide, heroin, and nicotine are concidered extreamly toxic, meaning their LD50 is in this range.
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Less than 5 mg/kg of body weight
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5 to 50 mg/kg of body weight
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50 to 500 mg/kg of body weight
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500 to 1000 mg/kg of body weight
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Explanation:
Detailed explanation-1: -LD50 can be calculated using the formula LD50 = ED50/3 x Wm x 10-4. It is expressed in mg/kg bw/d or milligram of a substance per kilo of body weight administered per day.
Detailed explanation-2: -LD50 is the abbreviation used for the dose which kills 50% of the test population. LC50 is the abbreviation used for the exposure concentration of a toxic substance lethal to half of the test animals. LD50 is expressed in milligrams per kilogram of body weight of the test animal (which must be mentioned).
Detailed explanation-3: -LD50. Similar term(s): lethal dose 50, median lethal dose, LC50. Definition: The amount of a chemical that is lethal to one-half (50%) of the experimental animals exposed to it.
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