NURSING ANM AND GNM

Detailed explanation-1: -Part I: Determining lethal dose Lethal dose (or LD50) refers to the amount of substance that kills 50 percent of a test sample. LD50 is expressed in mg/kg, or milligrams of substance per kilogram of body weight. Assume LD50 is the same for rats and humans. The LD50 for aspirin is 200 mg/kg (rat, oral).

Detailed explanation-2: -LD stands for “Lethal Dose". LD50 is the amount of a material, given all at once, which causes the death of 50% (one half) of a group of test animals.