NURSING ANM AND GNM

NURSING EXAM QUESTIONS

TOXICOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The ____ the LD50 measurement, the more toxic the substance
A
higher
B
lower
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -In general, the smaller the LD50 value, the more toxic the chemical is. The opposite is also true: the larger the LD50 value, the lower the toxicity. The LD50 gives a measure of the immediate or acute toxicity of a chemical in the strain, sex, and age group of a particular animal species being tested.

Detailed explanation-2: -LD50 is the abbreviation used for the dose which kills 50% of the test population. LC50 is the abbreviation used for the exposure concentration of a toxic substance lethal to half of the test animals. LD50 is expressed in milligrams per kilogram of body weight of the test animal (which must be mentioned).

Detailed explanation-3: -A low LD50 means the species is highly susceptible to the poison. The LD50 for a particular poison can vary greatly between different species of animals. Since LD50 is quoted in mg/kg of body weight, the amount of poison to kill an animal is a direct function of the species’ body weight. Other LD values.

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