NURSING EXAM QUESTIONS
TOXICOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The LD50 for aspirin is 400 mg/kg. How many grams of aspirin is lethal to a 220 pound person?
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15, 000 mg
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40, 000 mg
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100 mg
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23, 000 mg
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Explanation:
Detailed explanation-1: -LD50 can be calculated using the formula LD50 = ED50/3 x Wm x 10-4. It is expressed in mg/kg bw/d or milligram of a substance per kilo of body weight administered per day.
Detailed explanation-2: -LD stands for “Lethal Dose". LD50 is the amount of a material, given all at once, which causes the death of 50% (one half) of a group of test animals.
Detailed explanation-3: -It’s also important to note that LD50 test results are usually reported in milligrams of substance per kilogram of body weight (mg/kg).
There is 1 question to complete.