NURSING ANM AND GNM

NURSING EXAM QUESTIONS

TOXICOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The LD50 for Vitamin A is 2000mg/kg, how many chewable vitamin tablets would a 10kg child have to consume to reach the LD50 if each tablet contains 1mg of Vitamin A
A
2000 tablets
B
20000 tablets
C
1000 tablets
D
10000 tablets
Explanation: 

Detailed explanation-1: -LD50 less than 500 mg/kg indicates high toxicity. LD50 500 to 1, 000 mg/kg indicates moderate toxicity. LD50 1, 000 to 2, 000 mg/kg indicates low toxicity.

Detailed explanation-2: -The value of LD50 for a substance is the dose required to kill half the members of a tested population after a specified test duration. LD50 figures are frequently used as a general indicator of a substance’s acute toxicity. A lower LD50 is indicative of increased toxicity.

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