NURSING EXAM QUESTIONS
TOXICOLOGY
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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A
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B
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Both equal
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Does not depend on LC50
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Detailed explanation-1: -LC50 is defined as the concentration in air at which 50 percent of the test animals (rats or mice) died, usually within 1 hour. A substance is considered extremely toxic if it has an LD50 of less than 5 mgs/kg of animal body weight. To humans, this is the equivalent of a taste (less than 7 drops).
Detailed explanation-2: -LD50 less than 500 mg/kg indicates high toxicity. LD50 500 to 1, 000 mg/kg indicates moderate toxicity. LD50 1, 000 to 2, 000 mg/kg indicates low toxicity.
Detailed explanation-3: -Toxicity category I is highly toxic and severely irritating, Toxicity category II is moderately toxic and moderately irritating, Toxicity category III is slightly toxic and slightly irritating, Toxicity category IV is practically non-toxic and not an irritant.