NURSING ANM AND GNM

NURSING EXAM QUESTIONS

TOXICOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the substances below is the LEAST toxic?
A
Cola (LD50 = 140mg/kg)
B
Aspirin (LD50 = 200mg/kg)
C
Chlorine (LD50 = 850 mg/kg)
D
Vitamin A (LD50 = 2000 mg/kg)
Explanation: 

Detailed explanation-1: -There is an inverse relationship between product toxicity and LD50 value. Products with lower LD50 values are more hazardous and pose a greater risk than products with higher LD50 values (Figure 1). For example, product A with an LD50 = 400 mg/kg is more toxic than product B with an LD50 = 600 mg/kg.

Detailed explanation-2: -In general, the smaller the LD50 value, the more toxic the chemical is. The opposite is also true: the larger the LD50 value, the lower the toxicity. The LD50 gives a measure of the immediate or acute toxicity of a chemical in the strain, sex, and age group of a particular animal species being tested.

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