PATHOLOGY MCQ
BILIARY
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Optimal treatment for metastatic gallbladder carcinoma is
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gemcitabine monotherapy
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Yttrium-90 radioembolization
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capecitabine and infusional 5-flurouracil
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gemcitabine and cisplatin
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Explanation:
Detailed explanation-1: -The combination of gemcitabine and cisplatin achieved a response rate of 22% plus an additional disease stabilization rate of 26% giving an overall disease control rate of 48%. The median survival was 10.8 mo with a 1-year survival rate of 40% which were encouraging in the majority of patients with metastatic disease.
Detailed explanation-2: -Surgery is the preferred treatment for gallbladder cancer and offers the best chance for a cure. For tumors that have not spread beyond the gallbladder, the most effective procedure is called a radical cholecystectomy.
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