PATHOLOGY

Detailed explanation-1: -The tunica intima (New Latin “inner coat"), or intima for short, is the innermost tunica (layer) of an artery or vein. It is made up of one layer of endothelial cells and is supported by an internal elastic lamina. The endothelial cells are in direct contact with the blood flow.

Detailed explanation-2: -The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells.

Detailed explanation-3: -The tunica intima consists of a layer of endothelial cells lining the lumen of the vessel, as well as a subendothelial layer made up of mostly loose connective tissue.