PATHOLOGY

Detailed explanation-1: -Without the endoplasmic reticulum, the cell will not survive. Without rough ER the cell will not be able to synthesize new lysosomal enzymes, plasma membrane proteins, proteins for Golgi apparatus, and proteins essential for extracellular secretion.

Detailed explanation-2: -Proteins synthesized by the rough ER include the prominent milk protein casein, and whey proteins. These proteins are packaged into secretory vesicles or large micelles and travel through the Golgi network before fusing with the plasma membrane, releasing their contents into milk ducts.

Detailed explanation-3: -The endoplasmic reticulum can either be smooth or rough, and in general its function is to produce proteins for the rest of the cell to function. The rough endoplasmic reticulum has on it ribosomes, which are small, round organelles whose function it is to make those proteins.

Detailed explanation-4: -Alzheimer’s disease. Alzheimer’s disease (AD) is a progressive neurologic disorder characterized by a decline in cognitive processes, eventually leading to dementia. Parkinson’s disease. Amyotrophic lateral sclerosis.