PATHOLOGY

Detailed explanation-1: -When cells are injured, one of two patterns will generally result: reversible cell injury leading to adaptation of the cells and tissue, or irreversible cell injury leading to cell death and tissue damage. When cells adapt to injury, their adaptive changes can be atrophy, hypertrophy, hyperplasia, or metaplasia.

Detailed explanation-2: -Atrophy caused by pathology includes the following examples: This phenomenon occurs when there is a decrease in functional demand, resulting in muscle atrophy. This can be reversed by physical activity.

Detailed explanation-3: -If cells cannot adapt to the pathologic stimulus, they can die. This chapter will discuss cellular adaptation, cell injury, cellular accumulations, and cellular aging. Overview: The four basic types of cellular adaptation to be discussed in this section are hyperplasia, hypertrophy, atrophy, and metaplasia.