PATHOLOGY

PATHOLOGY MCQ

CELL DAMAGE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Apoptosis is ____
A
transformation of a cell into a malignant one
B
genetically programmed cell death
C
formation of embryonic antigent
D
irreversible cell damage
Explanation: 

Detailed explanation-1: -Apoptosis is the process of programmed cell death. It is used during early development to eliminate unwanted cells; for example, those between the fingers of a developing hand. In adults, apoptosis is used to rid the body of cells that have been damaged beyond repair. Apoptosis also plays a role in preventing cancer.

Detailed explanation-2: -Apoptosis, the major form of programmed cell death (PCD), is a physiological cell suicide process characterized by cell shrinkage, nuclear fragmentation, chromatin condensation and DNA fragmentation. As a type of non-traumatic cell death, apoptosis neither releases cell contents nor causes inflammation.

Detailed explanation-3: -The BCL-2 protein family plays a central role in the regulation of apoptosis. The BCL-2 family regulates apoptosis induction via control of the activation of caspases, apparently by a mechanism involving the release of mitochondrial cytochrome c.

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