PATHOLOGY

Detailed explanation-1: -Cancers is the result of loss of multicellular traits; thus, it is a disease of multicellularity. Caveat: Many of the so-called multicellular traits are also expressed by unicellular organisms and their loss can result in cancer-like mutants.

Detailed explanation-2: -Cancer represents a breakdown of molecular mechanisms evolved by multicellular life to impose constraints on cell growth, resulting in more “primitive” proliferative cellular phenotypes.

Detailed explanation-3: -Basics of cancer Cancer affects almost every multicellular organism on the tree of life, manifesting in slightly different ways across these species. Cancer-like phenomena involving abnormal proliferation have even been reported in fungi and bacteria.

Detailed explanation-4: -Cancer and its treatments can cause changes in the body Some cancers may block channels in the body and stop particular body systems working so well. Some cancers may cause changes in the body by pressing on surrounding body tissues or organs.

Detailed explanation-5: -Cancer is a normal part of being a large and complex multicellular organism. But that does not mean it’s inevitable.