PATHOLOGY MCQ
CELL DAMAGE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Cells pass through a G2 checkpoint before entering mitosis. Ideally, if DNA damage is detected, the cells do not enter mitosis until the damage is repaired. Why is DNA damage repaired before cells enter mitosis?
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So that another round of DNA synthesis does not have to take place
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So that the chromosomes can align at the metaphase plate during mitosis
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So that the cytoplasm can be divided equally between the two daughter cells
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So that healthy daughter cells are produced, allowing the organism to continue to grow.
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Explanation:
Detailed explanation-1: -Cells pass through a G2 checkpoint before entering mitosis. Ideally, if DNA damage is detected, the cells do not enter mitosis until the damage is repaired. Why is DNA damage repaired before cells enter mitosis? So that healthy daughter cells are produced, allowing the organism to continue growing.
Detailed explanation-2: -The G2 checkpoint ensures all of the chromosomes have been replicated and that the replicated DNA is not damaged before cell enters mitosis. The M checkpoint determines whether all the sister chromatids are correctly attached to the spindle microtubules before the cell enters the irreversible anaphase stage.
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