PATHOLOGY

Detailed explanation-1: -Also known as gap 1 phase, it is the first phase of the cell cycle in cell division. The cell is metabolically active and continuously grows in this phase of the cell cycle. However, no DNA replication takes place in this phase.

Detailed explanation-2: -During G1 phase, growth-dependent cyclin-dependent kinase (CDK) activity promotes DNA replication and initiates G1-to-S phase transition. CDK activation initiates a positive feedback loop that further increases CDK activity, and this commits the cell to division by inducing genome-wide transcriptional changes.

Detailed explanation-3: -During G1 phase, the cell grows in size and synthesizes mRNA and protein that are required for DNA synthesis. Once the required proteins and growth are complete, the cell enters the next phase of the cell cycle, S phase. The duration of each phase, including the G1 phase, is different in many different types of cells.

Detailed explanation-4: -DNA replication takes place during which phase of the cell cycle? Explanation: During the G1 phase the cell grows and also carries out normal cellular functions. In the synthesis (S) phase the DNA is replicated resulting in two copies of each of the chromosomes.