PATHOLOGY

PATHOLOGY MCQ

CELL DAMAGE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
During which stage of mitosis do the chromosomes line up down the middle of the cell?
A
Prophase
B
Anaphase
C
Metaphase
D
Telophase
Explanation: 

Detailed explanation-1: -Metaphase is a stage during the process of cell division (mitosis or meiosis). Normally, individual chromosomes are spread out in the cell nucleus. During metaphase, the nucleus dissolves and the cell’s chromosomes condense and move together, aligning in the center of the dividing cell.

Detailed explanation-2: -Metaphase. Chromosomes line up at the metaphase plate, under tension from the mitotic spindle. The two sister chromatids of each chromosome are captured by microtubules from opposite spindle poles. In metaphase, the spindle has captured all the chromosomes and lined them up at the middle of the cell, ready to divide.

Detailed explanation-3: -Answer and Explanation: The stage of mitosis in which chromosomes line up at the metaphase plate is known as metaphase. In this phase, the spindle fibers which attach to the chromosomes at the centromeres arrange the chromosomes along the metaphase plate.

Detailed explanation-4: -Metaphase. During metaphase, spindle fibers attach to the centromere of each pair of sister chromatids (see Figure below). The sister chromatids line up at the equator, or center, of the cell. This is also known as the metaphase plate.

Detailed explanation-5: -Metaphase follows prophase. During metaphase, the chromosomes align in the center of the cell at the equatorial plate and the spindle fibers attach to the centromeres of the chromosomes. Anaphase involves the retraction of the spindle fibers and the separation fo sister chromatids.

There is 1 question to complete.