PATHOLOGY

Detailed explanation-1: -In metastasis, cancer cells break away from the original (primary) tumor, travel through the blood or lymph system, and form a new tumor in other organs or tissues of the body. The new, metastatic tumor is the same type of cancer as the primary tumor.

Detailed explanation-2: -Spread through the bloodstream Cancer cells can go into small blood vessels and then get into the bloodstream. They are called circulating tumour cells (or CTCs). to help diagnose cancer and monitor treatment. The circulating blood sweeps the cancer cells along until they get stuck somewhere.

Detailed explanation-3: -Some cancers and cancer treatments can change the number of blood cells circulating in the blood. Cancers can spread by shedding cells into the bloodstream that may then settle in another part of the body.

Detailed explanation-4: -To metastasize, cancer cells break off from the primary tumor and travel through the blood or lymph to other organs. If someone is found to have cancer in their lymph nodes, it’s usually a bad sign that the cancer has or will soon spread to other parts of the body. Most cancer deaths are caused by metastatic cancer.

Detailed explanation-5: -Abstract: Cancer metastasis involves dissemination of malignant cells from the primary tumor, via local lymphatic vessels to gain access to systemic circulation, while evading the destruction by immune cells, followed by successful extravasation and initiation of malignant growth in the distant organ.