PATHOLOGY

Detailed explanation-1: -During interphase, the DNA of the chromosomes is replicated (during S phase). After DNA replication, each chromosome becomes composed of two identical copies (called sister chromatids) that are held together at the centromere until they are pulled apart during meiosis II (Figure 17.2.

Detailed explanation-2: -During S phase, genomic DNA is replicated and packaged into chromatin. The identical copies of each chromosome are known as sister chromatids, and they are tightly associated together through G2 phase and early mitosis.

Detailed explanation-3: -In the S phase (synthesis phase), DNA replication results in the formation of two identical copies of each chromosome-sister chromatids-that are firmly attached at the centromere region. At this stage, each chromosome is made of two sister chromatids and is a duplicated chromosome.

Detailed explanation-4: -These identical copies are known as sister chromatids. These sister chromatids are held together by the centromere. G2 Phase: During G2, the cell makes proteins that are used in cell division.

Detailed explanation-5: -Because each chromosome was duplicated during S phase, it now consists of two identical copies called sister chromatids that are attached at a common center point called the centromere.