PATHOLOGY

Detailed explanation-1: -Chromosome replication occurs during S Phase. The S phase of a cell cycle occurs during interphase, before mitosis or meiosis, and is liable for the synthesis or replication of DNA. S phase (Synthesis Phase) is the phase of the cell cycle during which DNA is replicated, occurring between the G1 phase and G2 phase.

Detailed explanation-2: -Then, at a critical point during interphase (called the S phase), the cell duplicates its chromosomes and ensures its systems are ready for cell division.

Detailed explanation-3: -During interphase (1), chromatin is in its least condensed state and appears loosely distributed throughout the nucleus. Chromatin condensation begins during prophase (2) and chromosomes become visible. Chromosomes remain condensed throughout the various stages of mitosis (2-5).

Detailed explanation-4: -The S phase is the second phase of interphase, during which the DNA of the chromosomes is replicated.

Detailed explanation-5: -A cell spends most of its time in what is called interphase, and during this time it grows, replicates its chromosomes, and prepares for cell division.