PATHOLOGY MCQ
CELL DAMAGE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Anaphase checkpoint, mitosis/metaphase checkpoint, and telophase checkpoint
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Interphase checkpoint, S phase checkpoint, and M phase checkpoint
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G1 checkpoint, G2 checkpoint, and S phase checkpoint
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G1 checkpoint, G2 checkpoint, and mitosis/metaphase checkpoint
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Detailed explanation-1: -There are many checkpoints in the cell cycle, but the three major ones are: the G1 checkpoint, also known as the Start or restriction checkpoint or Major Checkpoint; the G2/M checkpoint; and the metaphase-to-anaphase transition, also known as the spindle checkpoint.
Detailed explanation-2: -Cell-cycle checkpoints prevent the transmission of genetic errors to daughter cells. There exist three major cell-cycle checkpoints; the G1/S checkpoint, the G2/M checkpoint, and the spindle assembly checkpoint (SAC).
Detailed explanation-3: -1: Internal Checkpoints During the Cell Cycle: The cell cycle is controlled at three checkpoints. The integrity of the DNA is assessed at the G1 checkpoint. Proper chromosome duplication is assessed at the G2 checkpoint. Attachment of each kinetochore to a spindle fiber is assessed at the M checkpoint.
Detailed explanation-4: -G1 checkpoint is near the end of G1 (close to the G1/S transition). G2 checkpoint is near the end of G2 (close to the G2/M transition). Spindle checkpoint is partway through M phase, and more specifically, at the metaphase/anaphase transition.
Detailed explanation-5: -In the cell cycle, there are three major checkpoints-the G1 checkpoint, the G2 checkpoint, and the spindle checkpoint.