PATHOLOGY

Detailed explanation-1: -Necrosis is the pattern of cell death that occurs in response to injuries such as hypoxia, extremes of temperature, toxins, physical trauma, and infection with lytic viruses. The injury to a cell is said to be irreversible if it kills the cell. If the damage is a bit less, the injury is said to be reversible.

Detailed explanation-2: -Irreversible cell injury progresses and cannot return to normal state. Type of injury involved. Is typically the result of the beginning stages of lack of oxygen (hypoxia) and lack of blood flow to cells. It involves more agents such as viruses, genetic disadvantages, or immunological stimuli.

Detailed explanation-3: -Two patterns of reversible cell injury can be recognized under the light microscope: cellular swelling and cellular fatty change. Cellular swelling appears whenever cells are incapable of maintaining ionic and fluid homeostasis and is the result of loss of function of plasma membrane energy-dependent ion pumps.