PATHOLOGY MCQ
CELL DAMAGE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Mature nerve cells are in a resting state (G0); they no longer divide during mitosis
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Nerve damage disrupts the cell cycle at the G1 phase
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Nerve damage disrupts the cell cycle at the S phase
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Nerve damage prevents centrioles from being synthesized
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Detailed explanation-1: -Damage to the spinal cord rarely heals because the injured nerve cells fail to regenerate. The regrowth of their long nerve fibers is hindered by scar tissue and molecular processes inside the nerves. Scientists in now report that help might be on the way from an unexpected quarter.
Detailed explanation-2: -Generally, when you get injured, the body will heal itself with enough time. This is because most cells in the body are constantly regenerating. However, damaged nerve cells (neurons) in the central nervous system are unable to regenerate. Therefore, damage to the spinal cord is permanent.
Detailed explanation-3: -The spinal cord, part of our central nervous system, is an amazingly complex matrix of nerve cells and support cells. Following injury to the spinal cord, the damaged cells face anatomical, physiological, chemical, and immune system changes that hinder their attempts at regeneration.
Detailed explanation-4: -Which of the following most accurately explains why damaged nerve cells no longer regenerate? Mature nerve cells are in a permanent mitotic state; they no longer divide.