PATHOLOGY

PATHOLOGY MCQ

CELL DAMAGE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The human immunodeficiency virus (HIV) often infects and destroys CD4 T cells. These CD4 T cells are one of many kinds of white blood cells that are an important part of the immune system. The most common danger related to the destruction of CD4 T cells is-
A
an increase in the risk of high blood pressure
B
an increase in the threat of diseases caused by microorganisms and viruses
C
a decrease in the flow of blood to vital organs
D
a decrease in the amount of oxygen being transports to tissues
Explanation: 

Detailed explanation-1: -The hall mark of human immunodeficiency virus (HIV) infection is a gradual loss of CD4+ T-cells and imbalance in CD4+ T-cell homeostasis, with progressive impairment of immunity that leads ultimately to death. HIV infection in humans is caused by two related yet distinct viruses: HIV-1 and HIV-2.

Detailed explanation-2: -HIV binds to the CD4 molecule on the surface of helper T-cells and replicates within them. This results in destruction of CD4+ T-cells and leads to a steady decline in this population of T-cells.

Detailed explanation-3: -CD4 cells (also known as CD4+ T cells) are white blood cells that fight infection. CD4 cell count is an indicator of immune function in patients living with HIV and one of the key determinants for the need of opportunistic infection (OI) prophylaxis.

Detailed explanation-4: -HIV attacks and destroys CD4 cells. Without treatment, HIV may destroy so many CD4 cells that your immune system will have trouble fighting off infections. HIV is the virus that causes AIDS (acquired immunodeficiency syndrome). AIDS is the most serious stage of an HIV infection.

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