PATHOLOGY

Detailed explanation-1: -The nucleolus is a spherical structure found in the cell’s nucleus whose primary function is to produce and assemble the cell’s ribosomes.

Detailed explanation-2: -An area inside the nucleus of a cell that is made up of RNA and proteins and is where ribosomes are made.

Detailed explanation-3: -Eukaryote ribosomes are produced and assembled in the nucleolus. Ribosomal proteins enter the nucleolus and combine with the four rRNA strands to create the two ribosomal subunits (one small and one large) that will make up the completed ribosome (see Figure 1).

Detailed explanation-4: -The nucleolus is responsible for the production of ribosomes.

Detailed explanation-5: -The nucleolus is the largest nuclear organelle and is the primary site of ribosome subunit biogenesis in eukaryotic cells. It is assembled around arrays of ribosomal DNA genes, forming specific chromosomal features known as nucleolar organizing regions (NORs) which are the sites of ribosomal DNA transcription.