PATHOLOGY MCQ
CELL DAMAGE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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What are the two patterns of reversible cell injury visible under the light microscope?
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Cellular swelling and fatty change
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Swelling and disruption of lysosomes and fatty change
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Pyknosis and membrane blebbing
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Detailed explanation-1: -Two patterns of reversible cell injury can be recognized under the light microscope: cellular swelling and cellular fatty change. Cellular swelling appears whenever cells are incapable of maintaining ionic and fluid homeostasis and is the result of loss of function of plasma membrane energy-dependent ion pumps.
Detailed explanation-2: -Cellular swelling (synonyms: hydropic change, vacuolar degeneration, cellular edema) is an acute reversible change resulting as a response to nonlethal injuries. It is an intracytoplasmic accumulation of water due to incapacity of the cells to maintain the ionic and fluid homeostasis.
Detailed explanation-3: -By light microscopy, injured cells in an affected tissue are typically swollen or enlarged in size, sometimes with compression or displacement of internal organelles (e.g., the nucleus) or adjacent structures (e.g., other cells or connective tissue septa).