PATHOLOGY

Detailed explanation-1: -Karyolysis is the complete dissolution of nuclear components of a dying cell. However, the generation mechanism has not been clarified.

Detailed explanation-2: -Karyorrhexis is the destructive fragmentation of the nucleus of a daily cell whereby its chromatin is distributed irregularly throughout the cytoplasm. 3. Karyorrhexis is usually preceded by pyknosis. 4. Karyolysis is a complete dissolution of the chromatin of a dying cell due to enzymatic degradation by endonucleases.

Detailed explanation-3: -Pyknosis involves the shrinkage or condensation of a cell with increased nuclear compactness or density; karyorrhexis refers to subsequent nuclear fragmentation (Fig. 5-29, F). Pyknosis and karyorrhexis are degenerative changes that are often observed in nonseptic exudates.