PATHOLOGY

Detailed explanation-1: -If cells are no longer needed, they commit suicide by activating an intracellular death program. This process is therefore called programmed cell death, although it is more commonly called apoptosis (from a Greek word meaning “falling off, ‘’ as leaves from a tree).

Detailed explanation-2: -Necrosis has been thought to be an accidental or uncontrolled type of cell death rather than programmed.

Detailed explanation-3: -Until recently, necrosis has been considered a solely accidental and non-programmed cell death modality. However, extensive genetic and pharmacological studies have clearly demonstrated that cells can and do undergo programmed necrotic processes, such as necroptosis, pyroptosis, ferroptosis, and NETosis (Fig.