PATHOLOGY

PATHOLOGY MCQ

CELL DAMAGE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the first step of DNA replication?
A
DNA transfers its information to RNA through an amino acid
B
DNA molecule unzips along weak hydrogen bonds
C
Free nucleotides bond together in the correct sequence
D
A single stranded RNA molecule forms
Explanation: 

Detailed explanation-1: -The first step in DNA replication is to ‘unzip’ the double helix structure of the DNA? molecule. This is carried out by an enzyme? called helicase which breaks the hydrogen bonds? holding the complementary? bases? of DNA together (A with T, C with G).

Detailed explanation-2: -Helicase unzips & unwinds the 2 strands of DNA by breaking the weak hydrogen bonds between the nitrogen bases. Single-stranded binding proteins bind to the DNA strands to keep them separated. Enzymes unzip the DNA.

Detailed explanation-3: -The very first step in DNA replication is unzipping the double helix of the DNA molecule, the unwinding of DNA occurs by enzyme helicase and gyrase. After unwinding the DNA forms a replication fork and both the strands act as a template for the formation of new strands.

Detailed explanation-4: -DNA replication occurs through the help of several enzymes. These enzymes “unzip” DNA molecules by breaking the hydrogen bonds that hold the two strands together. Each strand then serves as a template for a new complementary strand to be created.

There is 1 question to complete.