PATHOLOGY MCQ
CELL DAMAGE
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
What is the main prerequisite for clearance at the G2 phase?
|
|
G1 checkpoint
|
|
|
G2 checkpoint
|
|
|
S checkpoint
|
|
|
M checkpoint
|
Explanation:
Detailed explanation-1: -The main prerequisite for clearance at the G2 checkpoint is accurate and complete DNA replication.
Detailed explanation-2: -The G2-phase checkpoint, also known as G2/M-phase checkpoint, has the function of preventing cells with damaged DNA, lasting from the G1 and S phases or generated in G2, from undergoing mitosis. The mechanisms acting during the G2-phase checkpoint converge on the inhibition of the mitotic complex CDK1-cyclin B.
Detailed explanation-3: -In order to pass the G2 checkpoint, all of the DNA must be duplicated and repaired before entering M phase.
There is 1 question to complete.