PATHOLOGY

Detailed explanation-1: -Metaphase is a stage during the process of cell division (mitosis or meiosis). Normally, individual chromosomes are spread out in the cell nucleus. During metaphase, the nucleus dissolves and the cell’s chromosomes condense and move together, aligning in the center of the dividing cell.

Detailed explanation-2: -In prophase I of meiosis, the homologous chromosomes form the tetrads. In metaphase I, these pairs line up at the midway point between the two poles of the cell to form the metaphase plate.

Detailed explanation-3: -Metaphase. During metaphase, spindle fibers attach to the centromere of each pair of sister chromatids (see Figure below). The sister chromatids line up at the equator, or center, of the cell. This is also known as the metaphase plate.

Detailed explanation-4: -During metaphase, chromosomes are organized on an equatorial plate. Metaphase is the stage of eukaryotic cell division when the chromosomes align in the middle of the cell.

Detailed explanation-5: -The chromosomes are held tightly by these forces constantly pushing and pulling on them. Metaphase can occupy a large portion of the total time of mitosis because chromosome alignment at the center of the cell on the metaphase plate acts as a checkpoint for progression into the next phase, anaphase.