PATHOLOGY

Detailed explanation-1: -When the cell increases in size, the volume increases faster than the surface area, because the volume is cubed where surface area is squared.

Detailed explanation-2: -As cells increase in size, their surface area-to-volume ratio decreases, meaning that their volume is increasing at a faster rate than their surface area.

Detailed explanation-3: -Cell growth refers to an increase in the total mass of a cell, including both cytoplasmic, nuclear and organelle volume.

Detailed explanation-4: -Seeing that the surface area to volume ratio of cells generally decreases as cells get larger, making the exchange of resources, waster and heat more and more difficult.

Detailed explanation-5: -As a cell grows bigger, the internal volume increases and thereby expands the cell membrane. In turn, the volume increases more rapidly than does the surface area. Thus, the relative amount of surface area available to pass materials to a unit volume of the cell decreases.