PATHOLOGY

Detailed explanation-1: -Steatosis is the accumulation of lipid droplets within hepatocytes and is considered pathologic when it affects more than 5% of hepatocytes. Steatosis initially exhibits an acinar zone 3 (centrilobular) distribution in adults.

Detailed explanation-2: -Overweight or obesity. Insulin resistance, in which your cells don’t take up sugar in response to the hormone insulin. High blood sugar (hyperglycemia), indicating prediabetes or type 2 diabetes. High levels of fats, particularly triglycerides, in the blood.

Detailed explanation-3: -Elevated plasma concentrations of glucose and fatty acids may promote hepatic fatty acid and triglyceride uptake and synthesis and impair -oxidation [19]. As a result, an accumulation of triglycerides in the liver will occurs, leading to hepatic steatosis.