PATHOLOGY

PATHOLOGY MCQ

CELL DAMAGE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Why is the S phase important for cell division?
A
To ensure there is enough DNA for the daughter cells
B
To make sure sister chromatids separate properly
C
To ensure cytokinesis takes place
D
To ensure there are no mutations
Explanation: 

Detailed explanation-1: -The S phase of a cell cycle occurs during interphase, before mitosis or meiosis, and is responsible for the synthesis or replication of DNA. In this way, the genetic material of a cell is doubled before it enters mitosis or meiosis, allowing there to be enough DNA to be split into daughter cells.

Detailed explanation-2: -The synthesis (S) phase of the cell cycle is of critical importance to precisely replicating the genomic information encoded in the nucleus of the cell. The G1 to S phase transition requires the activation and signaling of a number of specific components, including CDKs and Myc.

Detailed explanation-3: -The S phase of the cell cycle occurs before the interphase and is involved in DNA synthesis or replication. In this way, the genetic material of the cell is replicated before entering mitosis or meiosis, leaving enough DNA to divide into daughter cells.

Detailed explanation-4: -Upon entry into S phase, coordinated origin firing and replication progression ensure complete, timely, and precise chromosome replication. Both G1 and S phase progressions are controlled by master cell cycle protein kinases and ubiquitin ligases that govern the activity and abundance of DNA replication factors.

Detailed explanation-5: -The reason why it is important that the product of mitosis, the two daughter cells be genetically identical is to maintain the genetic identity of the somatic cell. Mitosis is a way for the daughter cells to grow and become the same cell type that will perform the same function for that cell.

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